Synthetic Biology and Engineering, Volume 1, Issue 2 (September 2023) – 7 articles

Cover Story (view full-size image):
The cell-free protein synthesis system offers unparalleled control for both fundamental research and bioengineering applications. Precise post-translational modifications are essential tasks to meet the increasing demands of accurate biomanufacturing of proteins. This review highlights the latest advancements and the confronted challenges in post-translational modifications within the cell-free protein synthesis system, outlining a prospective roadmap for cell-free biomanufacturing.  
Article Open Access
Fed-batch Self-regulated Fermentation of Glucose to Co-produce Glycerol and 1,3-propanediol by Recombinant Escherichia coli
  • Synthetic Biology and Engineering 2023, 1(2), 10008;
  • Guimin Liu   Cai Feng   Zhiwei Zhu   Yaqin Sun   Zhilong Xiu   Check
     22 May 2023

    As important bio-chemicals, glycerol and 1,3-propanediol (1,3-PDO) have been widely used in numerous fields, e.g., polymers, cosmetics, foods, lubrica...

    Article Open Access
    Nitrogen-controlled Valorization of Xylose-derived Compounds by Metabolically Engineered Corynebacterium glutamicum
  • Synthetic Biology and Engineering 2023, 1(2), 10009;
  • Lynn Schwardmann    Marielle Rieks   Volker F. Wendisch   Check
     31 May 2023

    The implementation of bioprocesses in an economically feasible and industrial competitive manner requires the optimal allocation of resources for a ba...

    Article Open Access
    Hydroxybenzoic Acid Production Using Metabolically Engineered Corynebacterium glutamicum
  • Synthetic Biology and Engineering 2023, 1(2), 10010;
  • Misa Doke   Mayumi Kishida   Yuuki Hirata   Mariko Nakano   Mayo Horita   Daisuke Nonaka   Yutaro Mori   Ryosuke Fujiwara   Akihiko Kondo   Shuhei Noda   Tsutomu Tanaka   Check
     19 Jul 2023

    Hydroxybenzoic acids (HBAs), including 4-HBA, 3-HBA, and 2-HBA, are valuable platform chemicals for production of commodity materials and fine chemica...

    Review Open Access
    Challenging Post-translational Modifications in the Cell-free Protein Synthesis System
  • Synthetic Biology and Engineering 2023, 1(2), 10011;
  • Kassidy B. Porche   Claire E. Lanclos   Yong-Chan Kwon   Check
     28 Jul 2023

    Post-translational modifications (PTMs) represent a cornerstone in the complexity of the proteome, significantly contributing to diversifying protein ...

    Review Open Access
    Dynamic Metabolic Control: From the Perspective of Regulation Logic
  • Synthetic Biology and Engineering 2023, 1(2), 10012;
  • Tian Jiang   Chenyi Li   Yuxi Teng   Jianli Zhang   Diana Alexis Logan   Yajun Yan   Check
     28 Aug 2023

    Establishing microbial cell factories has become a sustainable and increasingly promising approach for the synthesis of valuable chemicals. However, i...

    Review Open Access
    In Vitro BioTransformation (ivBT): Definitions, Opportunities, and Challenges
  • Synthetic Biology and Engineering 2023, 1(2), 10013;
  • Yi-Heng P. Job Zhang   Zhiguang Zhu   Chun You   Lingling Zhang   Kuanqing Liu   Check
     01 Sep 2023

    Great needs always motivate the birth and development of new disciplines and tools. Here we propose in vitro BioTransformation (ivBT) as a ne...

    Commentary Open Access
    Synthetic Biology Industry in China: Current State and Future Prospects
  • Synthetic Biology and Engineering 2023, 1(2), 10014;
  • Wei Luo   Yang Zhang   Jun Peng   Lishan Zhao   Check
     14 Sep 2023

    In this article, we provided an overview of the current state of the SynBio industry in China with a focus on its research and technology, its main ap...