Urban air quality reflects the combined effects of topography, built form, and emission sources, producing pronounced spatial and temporal variability in pollutant dispersion. This study investigates how urban morphological features-building density, green-space distribution, and transportation corridors-shape these dispersion patterns by deploying unmanned aerial vehicles (UAVs) equipped with Air Quality Index (AQI) sensors. Multi-altitude, high-resolution drone transects were conducted across contrasting urban settings to capture fine-scale pollutant distributions and their dynamics. The measurements reveal localized hotspots and zones of limited dispersion that align with variations in building layout, vegetation presence, and traffic intensity. Compared with fixed-site monitors, the UAV approach resolves vertical and horizontal gradients that are otherwise missed, providing complementary evidence of three-dimensional micro-scale heterogeneity. Taken together, the results indicate that decisions on urban design and infrastructure placement materially influence air-quality outcomes. These findings support the integration of UAV-based observations with conventional monitoring networks to inform targeted mitigation measures, exposure-aware mobility planning, and evidence-based strategies for public health and urban sustainability.