Found 611 results
Open Access
Article
28 July 2025Investigating Touch DNA Success Rates in Vehicle Sites for Hit-and-Run Casework
This study evaluated the effectiveness of Touch DNA recovery from four key vehicle contact points—steering wheel (SW), gear shift (GS), interior door handle (IDH), and exterior door handle (EDH)—in the context of hit-and-run forensic casework. 1769 samples were collected from 359 vehicles processed between 2020 and 2023. Statistically significant differences were observed in the quantity and quality of DNA recovered across these sites (p < 0.05). The steering wheel yielded the highest DNA success rates, followed by the gear shift, whereas the exterior and interior door handles demonstrated substantially lower recovery efficiency. These findings underscore the critical role of strategic sampling site selection in maximizing evidentiary outcomes. The results support prioritizing the steering wheel and gear shift as primary targets for DNA collection in vehicle-based investigations. The study highlights the practical utility of Touch DNA in linking individuals to vehicular crimes and calls for further research into alternative sampling techniques and contamination control measures to optimize forensic DNA recovery protocols in real-world hit-and-run scenarios.
Open Access
Article
24 July 2025Spermidine Dampens Inflammation by Directly Inhibiting Th17 Cytokine Production through a PRDX1 Associated Antioxidant Pathway
The activation of IL-17 signaling has been linked to the pathogenesis of many chronic, inflammatory lung diseases including cystic fibrosis. Through unbiased single-cell RNAseq screening, we found that IL-17+ T cells highly express Srm and Smox, which encode two key enzymes involved in spermidine synthesis, spermidine synthase and spermine oxidase respectively. Spermidine has been shown to reduce inflammation by regulating macrophage activation and balancing Th17/Treg differentiation; however its direct effects on Th17 cytokine production have not been carefully investigated. Here, using already differentiated Th17 cells from cultured mouse splenocytes, we found that exogenous spermidine directly inhibits IL-1β/IL-23-induced IL-17 production. Blockade of endogenous spermidine synthesis enhanced IL-17 production above native levels, further supporting the notion that spermidine is a direct regulator of cytokine secretion independent of differentiation. In vivo, spermidine alleviates lung inflammation in both Pseudomonas aeruginosa (PA) and LPS induced acute lung injury models. Further RNA-seq analysis suggests that spermidine suppression of Th17 cytokine production is mediated through its PRDX1-dependent antioxidant activity. Our data suggests that spermidine is a direct regulator of Type-17 T cell cytokine production and has potent anti-inflammatory effects against lung inflammation.
Open Access
Article
24 July 2025The Semantic Evolution and Cultural Cognition of the English Basic Color Term “Green”—A Diachronic Analysis Based on Cognitive Anthropology
Based on cognitive anthropology theory, this study systematically explores the semantic evolution path and cultural cognitive mechanisms of the English basic color term “green”. Through analyzing the etymology, semantic extension, and usage frequency of the color term “green” in English, the study reveals its complex transformation from a natural attribute to a socio-cultural symbol. The results indicate that the semantic evolution of the color term “green” is influenced not only by the universality of human visual cognitive mechanisms, but also profoundly reflects the ecological concepts, political ideologies, and socio-psychological characteristics present in English culture. These findings provide a new analytical dimension for research on color terms and deepen the understanding of the relationship between language and culture.
Open Access
Article
24 July 2025Anthropological Pathways to Cultural Understanding: “Language Learning Circles in Early Childhood Bilingual Education in the U.S.A.”
This article presents a literature review that employs an anthropological perspective to investigate the role of Language Learning Circles (LLCs) in fostering early bilingual development and cultural identity among Hispanic children in the United States. As the Spanish-speaking population grows, the need for culturally grounded language education becomes more urgent. LLCs, rooted in educational and anthropological traditions, serve as structured, dialogic spaces where language learning is tied to cultural practices such as storytelling, music, and rituals. Drawing on theories of language socialization, cultural artifacts, and communicative competence, this paper situates LLCs within broader anthropological discussions on identity, belonging, and community building. By highlighting how LLCs promote linguistic diversity, foster cross-cultural understanding, and employ inclusive teaching methods, the article offers insights into how early childhood education can serve as a powerful site for cultural transmission and resistance. Special focus is given to the implications for Hispanic families navigating bilingualism and educational equity in the U.S.
Open Access
Article
23 July 2025Harnessing Nature’s Colours: Experimental and Computational Insights into Bixa orellana Pigments for Next-Generation Dye-Sensitized Solar Cells
The potential of Bixa orellana (annatto) pigments, specifically bixin and norbixin, as sensitizers for dye-sensitized solar cells (DSSCs) was investigated. The pigments were extracted using various solvents (acetone, methanol, ethanol, and hexane), and their optical and photo-electrical properties were investigated using UV-Vis spectroscopy and photoelectrical analysis. Results indicate that acetone extract (a-AP) exhibited the highest power conversion efficiency (PCE) of 0.786%, attributed to its broad absorption spectrum and optimal electronic properties. Quantum chemical calculations revealed that both bixin and norbixin exhibit favourable frontier orbital energies and energy gaps, making them well-suited for efficient electron injection and light absorption. These findings position Bixa orellana pigments as promising, eco-friendly alternatives to conventional synthetic sensitizers, offering a pathway toward more sustainable, locally adaptable, and efficient solar energy harvesting.
Open Access
Article
23 July 2025Evaluation and Modeling of Long-Term Endurance Measurement on Electric Double Layer Capacitors to Increase Reliability of Lifetime Predictions
Sustainability in the electrical industry and product reliability are fundamentally dependent on product lifetime predictions. Long-term DC voltage endurance measurements at two different temperatures on various commercial electric double-layer capacitors are presented, discussed, and used to develop a deterioration model suitable for estimating lifetime. Capacitors were tested under constant voltage for approximately 1 year at 65 °C and about 4 years at room temperature. To describe the deterioration in terms of capacitance and the equivalent series resistance, a phenomenological model is proposed and tested against measurements taken at room temperature. The proposed model is based on a general exponential relation with a time-dependent deterioration rate. The model is tested against long-term measurements with constant and time-dependent temperature acceleration factors. Analysis of capacitance and equivalent series resistance measurements shows a time or deterioration dependence in the temperature acceleration factor and different phases of deterioration.
Open Access
Communication
22 July 2025The Importance of Methods in Assessing Conservation Status of Abundant Fish Species through Genetic Diversity Estimates
This study compares the accuracy of two genomic approaches in estimating genetic diversity levels, which could be useful for informing species conservation assessments of abundant, exploited fish species. The first approach (SNP-calling-based) is the commonly used pipeline of SNP calling followed by SNP filtering at a determined Minor Allele Frequency (MAF). The second approach (genotype-likelihood-based) does not perform SNP calling but estimates the Site Spectrum Frequency (SFS) based on alignment quality and sample size. The results show up to two-fold differences in the magnitude of the estimated nucleotide diversities among the analyzed datasets. The SNP-calling-based approach produces overestimates when missing data are considered in the analysis and shows pronounced deviations of the SFS towards high-frequency SNPs when filtering by MAF > 5%. The genotype likelihood-based approach showed that nucleotide diversity estimates significantly deviated from neutral expectations, as expected based on the known history of the case-study fish population analyzed here, regardless of whether missing data were considered. In contrast, the SNP-calling-based approach only shows this expected difference when no missing data are included and no MAF filtering is performed. Overall, the results indicate that using the SNP-calling-based approach may hide the effects of population size declines in abundant exploited fish species, while genotype-likelihood-based estimates of nucleotide diversity can effectively contribute to informing conservation assessments.
Open Access
Article
21 July 2025Rapid Production
of High-Titer d -Mannitol and
Gluconate Catalyzed by a Combination of Whole-Cell and an Enzyme at High
Temperatures
Open Access
Review
21 July 2025Fuel Oil Combustion Pollution and Hydrogen-Water Blending Technologies for Emission Mitigation: Current Advancements and Future Challenges
In recent years, researchers have focused on exploring alternative fuel technologies that enhance engine performance and combustion efficiency while reducing nitrogen oxide (NOx) and particulate matter (PM) emissions. Water-diesel emulsified fuel, which requires no engine modifications, has emerged as a critical pathway for cleaner diesel engine applications. This review systematically examines the combustion characteristics, emission performance, and energy efficiency of emulsified fuels in compression ignition (CI) engines. Studies indicate that compared to conventional pure diesel, emulsified fuels significantly optimize combustion processes through micro-explosion phenomena, shorten ignition delays, and improve combustion efficiency. Notably, NOx and PM emissions are simultaneously reduced, effectively resolving the traditional trade-off dilemma between pollutant reduction targets. Emulsified fuel exhibits comparable power output and fuel consumption rates to those of pure diesel, while delivering enhanced environmental benefits. Additionally, innovative technologies such as hydrogen nanobubbles further enhance combustion dynamics by improving fuel atomization and radical generation, though challenges persist in stabilizing non-aqueous nanobubbles and scaling up production. Despite ongoing advancements in policy incentives (e.g., green hydrogen subsidies) and combustion mechanism research, industrial adoption of emulsified fuels still faces technical hurdles, including equipment corrosion and issues with long-term storage stability issues. In conclusion, water-based emulsified fuels and hydrogen-water blending technologies provide efficient and low-cost transitional solutions for reducing diesel engine emissions, with their multi-component synergistic optimization mechanisms laying a theoretical and practical foundation for future clean fuel development.
Open Access
Article
21 July 2025The Intergovernmental Networks of Ecological Protection Policies Issuing Entities in the Source Region of the Yangtze River: A Case Study of Qinghai Province
Ecological conservation and governance play key roles in constructing an ecological civilization society, while intergovernmental cooperation provides new perspectives for cross-regional ecological governance. We employed a social network analysis (SNA) method to examine 110 published ecological policies from 2000 to 2024 in the Source Region of the Yangtze River (SRYR). The study has three key findings. Firstly, intergovernmental collaborative policies on ecological protection showed an upward trend, with intra-provincial collaborations within Qinghai Province being the most frequent. Secondly, four collaboration models were demonstrated, namely: national ministries, national and provincial, cross-provincial and intra–provincial collaborations. National agencies and Qinghai provincial agencies collaboratively set objectives, which Qinghai operationalizes with incentive-constraint measures. Then, the targeted guidelines were launched by national and provincial authorities. Afterward, cross–provincial agreements and mechanisms facilitate joint actions. Thirdly, we revealed the hierarchical structures, including a national network, two central-local sub-networks, three-tier inter-provincial partnerships, and four regional sub-clusters. Core actors include national ministries that coordinate cross-departmental efforts. The Qinghai provincial government serves as a central-local hub. It maintains strong transboundary ties with Aba and Ganzi Prefectures of Sichuan Province. Provincial departments such as ecology and environment, forestry and grasslands, and finance lead intra-provincial collaborations. These findings offer new insights for integrating multi-level governance in ecological protection and ecological civilization construction.
