Topic Introduction

Synthetic biology, an interdisciplinary field that combines engineering, biology, and computational approaches, offers a powerful tool for the sustainable production of biochemicals and biofuels from renewable resources. By manipulating and engineering genetic circuits, synthetic biology enables the optimization of metabolic pathways in microorganisms or with cell free systems for the synthesis of desired chemical compounds. This has led to the creation of novel and valuable biochemicals, such as pharmaceuticals and flavors, as well as the development of cost-effective and environmentally friendly biofuels. This special topic collection will highlight the latest advancements in synthetic biology for biochemicals and biofuels production, covering a broad range of topics, including the development of non-conventional microbial chassis, the engineering of novel carbon metabolisms (C1 substrate, lignin, etc.), the design of innovative pathways, the development of high-value chemicals, the enhanced production of biofuels, and the integration or hybridization of synthetic biology with other emerging technologies and innovative processes. Additionally, this special issue welcomes reviews and perspectives on the challenges and opportunities for the future of this exciting research field. 

Keywords

• Synthetic Biology
• Genome Editing
• CRISPR
• Biofuels
• Biochemicals
• Non-conventional Microorganisms
• Cell Free System
• Carbon Metabolism
• Metabolic Pathways
• Carbon Sequestration
• Environmental Sustainability