Rates of anxiety and depression in children and adolescents have steadily risen over the past decade, and the arrival of COVID-19 exacerbated existing psychological problems for many youth. In the context of these increased rates and the pandemic lockdown, telepsychology, including virtual assessment, evolved as a cornerstone of mental health practice. There are salient benefits to telepsychology, most notably its convenience and accessibility, which have contributed to its expanded application across different types of problems and populations. At the same time, it can pose challenges in acquiring a comprehensive picture of client functioning. This article presents a case study of an adolescent with combined anxiety and depression who was referred for teletherapy during COVID-19, with an emphasis on the assessment intake. Results from a multi-method approach to the assessment are provided along with a brief discussion of treatment and future implications for the practice of telepsychology with youth and families.