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Open Access

Case Report

11 August 2025

Transition to Hydrogen Aviation: A 2030–2050 Scenario Performance Analysis for an Airline

This study presents a realistic hypothetical scenario-based analysis of an airline’s transition from kerosene to hydrogen propulsion between 2030 and 2050, under a Techno-Economic Environmental Risk Assessment (TERA) framework. Two scenarios are modelled: a baseline fleet scenario using only conventional CMRT and CLRT aircraft, and a hydrogen transition scenario that introduces hydrogen-powered Airbus ZEROe and HVLMR aircraft starting in 2035. Using detailed aircraft (Orion from Cranfield) and jet engine (TURBOMATCH from Cranfield) performance simulations across 85 global routes, fuel consumption, energy demand, emissions, and operating costs are assessed. Strategic hydrogen hubs at London Heathrow and Neom Bay enable network feasibility for aircraft with limited range. Key findings show that the hydrogen scenario reduces total fuel mass consumption by approximately 28%, due to hydrogen’s high specific energy, and cuts CO2 emissions by 49%, assuming green hydrogen usage. However, it also results in a 9.6% increase in energy demand and ~15–20% higher cumulative operating costs, driven by greater depreciation, maintenance, and fuel price premiums. While the hydrogen transition introduces higher upfront and operational costs, it offers long-term environmental benefits and compliance with net-zero aviation goals. The study concludes that hydrogen aviation holds strategic promise but faces significant technical challenges, particularly due to the immaturity of hydrogen storage and propulsion systems. Realising this potential will require coordinated investment in infrastructure, policy support, and adaptive route planning.

Keywords: Hydrogen aviation; Sustainable aviation fuel; Techno-economic analysis; Environmental impact; Airline fleet transition; Aircraft performance simulation; Airline finance; Airline investment; Net-zero aviation
Clean Energy Sustain.
2025,
3
(3), 10011; 
Open Access

Communication

05 August 2025

Autoimmune Adverse Events Following Immunization

Adverse events (AEs) following immunization can include autoimmune AEs for some vaccines and combinations. This study retrospectively examines autoimmune AEs to detect safety signals for vaccines and concomitantly administered vaccines in the Vaccine Adverse Event Reporting System (VAERS) database. This study focuses on which vaccines were administered or coadministered for retrospective analysis of analyzed autoimmune AEs. Observed results include multiple autoimmune AE safety signals: human papillomavirus (HPV) Cervarix, HPV Gardasil, hepatitis (Hep) A + Hep B (Twinrix), Lyme disease (LYMErix), coadministered COVID-19 Moderna + Pfizer-BioNTech, Hep B (Engerix-B), and others. Identified arthritis AE safety signals include Lyme disease (LYMErix), rubella (Meruvax II), HPV (Cervarix), Anthrax (Biothrax) + Smallpox (Dryvax), and more. Coadministered DTaP + HepB + IPV (Pediarix) + Hib (Pedvaxhib) + Pneumococcal (Prevnar13) + Rotavirus (Rotarix) may be exhibiting synergy AE rate for eczema AEs. Thirty five influenza vaccines were observed with Guillain–Barré syndrome (GBS) AE safety signals, plus additional safety signals for multiple other vaccines. influenza (H1N1 monovalent) (GSK) exhibits a very high rate for narcolepsy AEs.

Keywords: Autoimmune; Adverse events; Arthritis; Complex regional pain syndrome; Guillain-Barré syndrome; Henoch Schonlein purpura; Postural orthostatic tachycardia syndrome; Systemic lupus erythematosus
Immune Discov.
2025,
1
(3), 10010; 
Open Access

Article

29 July 2025

Air Conditioning Heat Exchanger Intelligent Production Line: Design Methodologies and Applications

As a key component in modern building environmental control systems, the production quality and performance of multi-split central air conditioning systems directly influence the comfort, energy efficiency, and operational stability of buildings. However, the current manufacturing process primarily relies on a combination of traditional manual labor and automated equipment, resulting in low efficiency, high energy consumption, and limited automation. This paper first presents an optimized design for an intelligent manufacturing production line for multi-split central air conditioning heat exchangers to address these issues. It details the design of key systems for the intelligent production line and ensures continuous production and processing. Additionally, the paper analyzes the production process of the intelligent manufacturing line, with particular emphasis on the mechanism of the heat exchanger tube expansion process. Furthermore, it designs the fixture structure of the transfer robot for each process in the production line and discusses the principles of workpiece positioning and clamping. Utilizing technologies such as sensor networks, PLC, and industrial Ethernet, the system completes the closed-loop process of perception, transmission, analysis, decision-making, and execution within the production line, enabling transparency, fault predictability, and automated management. The results show that the intelligent assembly production line has significantly improved the assembly efficiency, achieving a 300% increase in the daily production capacity of a single line. While enabling the continuous and intelligent production of multi-split central air conditioning heat exchangers.

Keywords: Central air conditioner; Heat exchanger; Production line; Process flow fixture; Intelligent control; Robot
Intell. Sustain. Manuf.
2025,
2
(2), 10024; 
Open Access

Article

28 July 2025

Investigating Touch DNA Success Rates in Vehicle Sites for Hit-and-Run Casework

This study evaluated the effectiveness of Touch DNA recovery from four key vehicle contact points—steering wheel (SW), gear shift (GS), interior door handle (IDH), and exterior door handle (EDH)—in the context of hit-and-run forensic casework. 1769 samples were collected from 359 vehicles processed between 2020 and 2023. Statistically significant differences were observed in the quantity and quality of DNA recovered across these sites (p < 0.05). The steering wheel yielded the highest DNA success rates, followed by the gear shift, whereas the exterior and interior door handles demonstrated substantially lower recovery efficiency. These findings underscore the critical role of strategic sampling site selection in maximizing evidentiary outcomes. The results support prioritizing the steering wheel and gear shift as primary targets for DNA collection in vehicle-based investigations. The study highlights the practical utility of Touch DNA in linking individuals to vehicular crimes and calls for further research into alternative sampling techniques and contamination control measures to optimize forensic DNA recovery protocols in real-world hit-and-run scenarios.

Keywords: Forensic genetics; Forensic science; DNA profiling; Trace DNA; Touch DNA; DNA recovery; Hit-and-run casework; Vehicle DNA collection; Forensic casework; DNA success rate
Open Access

Article

21 July 2025

The Intergovernmental Networks of Ecological Protection Policies Issuing Entities in the Source Region of the Yangtze River: A Case Study of Qinghai Province

Ecological conservation and governance play key roles in constructing an ecological civilization society, while intergovernmental cooperation provides new perspectives for cross-regional ecological governance. We employed a social network analysis (SNA) method to examine 110 published ecological policies from 2000 to 2024 in the Source Region of the Yangtze River (SRYR). The study has three key findings. Firstly, intergovernmental collaborative policies on ecological protection showed an upward trend, with intra-provincial collaborations within Qinghai Province being the most frequent. Secondly, four collaboration models were demonstrated, namely: national ministries, national and provincial, cross-provincial and intra–provincial collaborations. National agencies and Qinghai provincial agencies collaboratively set objectives, which Qinghai operationalizes with incentive-constraint measures. Then, the targeted guidelines were launched by national and provincial authorities. Afterward, cross–provincial agreements and mechanisms facilitate joint actions. Thirdly, we revealed the hierarchical structures, including a  national network, two central-local sub-networks, three-tier inter-provincial partnerships, and four regional sub-clusters. Core actors include national ministries that coordinate cross-departmental efforts. The Qinghai provincial government serves as a central-local hub. It maintains strong transboundary ties with Aba and Ganzi Prefectures of Sichuan Province. Provincial departments such as ecology and environment, forestry and grasslands, and finance lead intra-provincial collaborations. These findings offer new insights for integrating multi-level governance in ecological protection and ecological civilization construction.

Keywords: Intergovernmental relations; Ecological protection policy; Issuing entities; Social network analysis; The source region of the Yangtze River
Ecol. Civiliz.
2025,
2
(4), 10011; 
Open Access

Article

15 July 2025

Exploring the Sustainable Path of Rural Governance: An Empirical Study on Digital Technology Empowering the “Fengqiao Experience” Model in the New Era

Understanding digital technology and digital inclusive finance in rural governance is key to exploring the sustainable development path of rural governance in China. This study constructs a multidimensional index evaluation system for the “Fengqiao Experience” rural governance model in the new era, measures the model’s rural governance level in 30 provinces in China (2011–2022), and empirically assesses digital technology’s impact on rural governance and its mechanism. The results are as follows: (1) During the sample survey period, the rural governance level of digital technology and “Fengqiao Experience” in 30 provinces in China has improved year by year. (2) Benchmark returns to reality and digital technology significantly promotes the improvement of rural governance levels, which remains valid after using GLS, replacing core explanatory variables, excluding the impact of the epidemic, and excluding municipalities directly under the central government. (3) Digital inclusive finance plays an intermediary role in the digital technology process, enabling rural governance. (4) Digital technology’s impact on rural governance has significant spatial spillover characteristics. Such technology helps improve the level of rural governance both locally and in surrounding areas. This study contributes to the understanding of the mechanism, effect, and regional differences of digital technology-enabled rural governance.

Keywords: Digital technology; Rural governance; Fengqiao Experience; Governance entities; Governance approaches
Rural Reg. Dev.
2025,
3
(4), 10012; 
Open Access

Review

09 July 2025

Muti-Energy Field-Assisted Grinding of Hard and Brittle Materials: Tools, Equipment and Mechanisms

Hard, brittle and difficult-to-machine materials are prone to surface cracks, subsurface damage and other defects in the traditional grinding process, accompanied by low processing efficiency and severe tool wear. As a new type of processing technology, energy field-assisted grinding provides a new approach for the efficient and high-quality processing of hard and brittle materials. This paper reviews the latest research progress of muti-energy field-assisted grinding from aspects such as the types and selection of grinding tools, processing equipment and physical-chemical coupled mechanisms. Firstly, micro-grinding tools are classified based on different surface structures and coating materials, with the aim to enhance processing efficiency, improve the surface quality and geometric accuracy of workpieces, and reduce tool wear. Secondly, the processing mechanisms, parameter selection and current difficulties faced by four energy field-assisted grinding methods, including laser-assisted grinding, electrochemical-assisted grinding, magnetic-assisted grinding and ultrasonic field-assisted grinding, are discussed under both chemical and physical effects. Thirdly, different equipment and auxiliary devices developed for energy field-assisted grinding have been introduced, providing reliable platforms for the distribution design and efficient regulation of the energy field. Finally, the cutting-edge progress, main challenges and development trends of energy field-assisted grinding are prospected, illustrating the great potential of this technology in fields such as aerospace, electronics, and optical components.

Keywords: Hard and brittle materials; Microstructure; Energy field-assisted grinding; Chemical-physical coupling effect
Intell. Sustain. Manuf.
2025,
2
(2), 10022; 
Open Access

Article

30 June 2025

Hydrodynamic Analysis of Offshore Floating Photovoltaic Structure with Elastic Connection

Offshore Floating Photovoltaic structure (OFPV) represents a promising solar energy technology characterized by high conversion efficiency and suitability for large-scale deployment. However, the safety and economic synergy problems of floating structures restrict the industrialization and large-scale development of OFPV. We propose a novel OFPV with elastic connection and modularizable HDPE float blocks. The numerical wave tank is established by the turbulence model in FLOE-3D, based on the Navier-Stokes equations. Hydrodynamic analysis of the OFPV is conducted by using the Generalized Mode-Order (GMO) approach. Furthermore, the dynamic responses and mooring loads of the OFPV with elastic and rigid connections are compared. The results show that the average pressure of the photovoltaic support structure with the elastic connection is positively correlated with the wave height. The tension value of the elastic cable is higher at the outermost peak tension. The OFPV with the elastic connection structure has more obvious advantages in extreme wave state conditions than the rigid connection. This study provides theoretical support for the design and engineering application of OFPV.

Keywords: OFPV; Elastic connection; Rigid connection; Hydrodynamic performance analysis
Mar. Energy Res.
2025,
2
(2), 10011; 
Open Access

Article

30 June 2025

Review of Cyprinodontiform Fishes in the Upper Congo Drainage with Descriptions of Four New Species of Seasonal Nothobranchius (Nothobranchiidae) and a New Species of ‘Lacustricola’ Lampeye (Procatopodidae) in South-Eastern DR Congo

The cyprinodontiform fish fauna of the Bangweulu–Mweru and Upper Lualaba freshwater ecoregions, situated in the uppermost Congo River drainage, has been reviewed. This study introduces four newly described species of seasonal Nothobranchius killifish and a novel species of lampeye belonging to the genus ‘Lacustricola’. Nothobranchius iridescens, new species, from the Kafila system in the Lufira drainage, is characterized in male colouration by anal fin with irregular red-brown spots and stripes, creating two irregular submedial and medial bands and with broad yellow subdistal band; and a caudal fin with a slender light blue subdistal band, densely marked with irregular red spots, and narrow dark brown distinct distal margin. Nothobranchius katemomandai, new species, from the Kay system in the upper Lualaba drainage, is characterized in male colouration by an anal fin with narrow brown submedial band, followed by a slender yellow band, a slender red-brown band and a slender dark brown distal band; and a caudal fin with brown spots proximally and medially, and with slender white to light blue subdistal band and a narrow dark grey distal band. Nothobranchius marmoreus, new species, from the Lufukwe system in the Lake Mweru basin, is characterized in male colouration by a body with irregular red-brown patches and stripes, forming a marble-like mottled pattern; and anal and caudal fins with slender yellow to amber subdistal band and broad dark brown distal band. Nothobranchius dubieensis, new species, from the Lubule system in the Luvua drainage, is characterized in male colouration by an anal fin with narrow dark brown submedial band, narrow yellow and orange medial bands, narrow white subdistal band, and slender dark brown distal band; and a caudal fin with irregular red-brown spots and stripes proximally and medially, followed by an irregular narrow red-brown subdistal band and slender white distal band, and with interrupted red-brown fin tips. ‘Lacustricolagemma, new species, from the Kay system in the upper Lualaba drainage, is characterized by a pattern of iridescent, diamond-shaped, light blue spots in scale centres below mid-longitudinal series on posteroventral portion of flank; median fins yellow to hyaline, with dark grey stripes perpendicular to fin rays; dorsal fin with light blue distinct margin; anal fin with dark grey margin. Analysis of mitochondrial COI gene sequences revealed that the five new species represent phylogenetically distinct lineages. These findings not only underscore their genetic uniqueness but also confirm their placement within the Nothobranchius brieni species group and the genus ‘Lacustricola’. Species of the genus Nothobranchius complete their seasonal life cycle in ephemeral natural habitats within freshwater wetlands, while ‘Lacustricola’ species migrate to breed in flooded areas of shallow, typically seasonal wetland habitats at the onset of the rainy season. These wetlands are highly vulnerable to a variety of human-induced stressors and threats, including agricultural cultivation, water extraction, urban expansion resulting in land-use pressure, and increased pollution, particularly from industrial activities such as mining. Therefore, it is essential to protect the integrity of these unique aquatic habitats throughout all the seasons of the year to maintain healthy wetland ecosystems and safeguard the distinctive seasonal freshwater biodiversity they support.

Keywords: Bangweulu–Mweru freshwater ecoregion; Barcoding; Conservation; Killifish; Upper Lualaba freshwater ecoregion
Ecol. Divers.
2025,
2
(2), 10006; 
Open Access

Article

27 June 2025

Non-Invasive Evaluation by the HEMOTAGTM Recording Device to Tailor Treatment of Acutely Decompensated Heart Failure

This study evaluated the clinical utility of the HEMOTAG™ recording device—A non-invasive, wearable system that measures cardiac time intervals (CTIs)—in managing patients with acutely decompensated heart failure (ADHF). The prospective, single-center study enrolled 105 patients, including those hospitalized with ADHF and a control group with non-HF-related conditions. Daily measurements of isovolumetric contraction time (IVCT), a key CTI marker, were collected using the HEMOTAG device and compared with NT-proBNP levels obtained on admission and day 3. Among ADHF patients, IVCT decreased in parallel with NT-proBNP levels, indicating volume status improvement with therapy. In contrast, the control group showed no significant change in IVCT or NT-proBNP. An IVCT ≥ 40 ms demonstrated strong sensitivity and specificity to detect ADHF (NT-proBNP ≥ 1800 pg/mL). These findings suggest that IVCT trends measured by HEMOTAG correlate with short-term treatment response in ADHF and could offer a non-invasive method to guide heart failure management. The technology demonstrated feasibility, safety, and clinical relevance, supporting its potential role in future remote management strategies.

Keywords: Heart failure; Acutely decompensated heart failure (ADHF); Isovolumetric contraction time (IVCT); NT-proBNP; Cardiac time intervals (CTIs); Remote management; Wearable device; Non-invasive monitoring; Congestion
Cardiovasc. Sci.
2025,
2
(3), 10007; 
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