Holistic decarbonisation requires collaborative efforts and substantial investments across diverse economic sectors. This study introduces an innovative national approach, blending technological insights and philosophical considerations to shape decarbonization policies and practices. Libya is the case study. The proposed framework involves submersible power stations with continuous-duty helium closed-cycle gas turbines to supply electricity demand and hydrogen. Extensive national data is analysed, incorporating factors such as sectoral consumption, sea temperature, and port locations. An analytical model is developed, providing a valuable foundation for realistic decarbonization scenarios. The model aims to maintain the benefits of current energy consumption, assuming a 2% growth rate, while assessing changes in a fully green economy. The results offer qualitative and quantitative insights on hydrogen use and an expected rise in electricity demand. Two scenarios are examined: self-sufficiency and replacing oil exports with hydrogen exports. This study provides a quantitative perspective on decarbonization, focusing on a submersible helium closed cycle gas turbine concept resistant to natural disasters and proliferation. Findings underscore the substantial changes and investments needed for this transition, identifying primary needs of 27 GW or 129 GW for self-sufficiency and exports, respectively. This foundational analysis marks the start of research, investment, and political agendas toward decarbonization.
Nickel-based alloys has important application value in modern industrial field, but there are a lot of problems that are difficult to solve in traditional processing, and it is a typical difficult-to-process material. In order to improve the machinability of nickel-based alloys, scholars try to use a variety of non-traditional processing methods to explore and study the processing of nickel-based alloys. In these studies, ultrasonic vibration assisted processing technology and minimum quantity lubrication (MQL) processing technology can achieve remarkable results. The intermittent separation cutting characteristics of ultrasonic vibration assisted processing technology can improve the processing quality by changing the tool path, while minimum quantity lubrication processing technology can improve the lubrication effect of cutting, combining ultrasonic vibration assisted MQL processing leverages the benefits of both methods, resulting in improved machinability and expanded application of nickel-based alloys. Summarize the current research status on the machining mechanism of nickel-based alloys assisted by ultrasonic vibration and micro lubrication, and anticipate its developmental trends. This provides a reference for future research on the efficient machining mechanisms and practical applications of nickel-based alloys.
Despite that ocean current energy is one of the promising sources of electricity produced in the ocean, the development of ocean current energy is far behind compared to other ocean energy due to the low efficiency and high cost of installation and maintenance. Among many converting devices, the Savonius turbine has been proven to be effective and competitive in harnessing ocean current energy. The primary purpose of the present study is to search for the optimum shape of a Savonius rotor based on CFD simulation (Star-CCM+). A Savonius turbine composed of two rotating cup-shaped rotors is selected as a numerical model. We focus on the effect of two geometry parameters such as the overlap and gap ratio on the power coefficient. Throughout the parametric study, the shape of a Savonius rotor affects the power performance, and two geometry parameters with an overlap ratio of 0.15 and a gap ratio of −0.03 are found to be the optimum design. It demonstrates stable performance within the wide TSR (Tip Speed Ratio) range of 0.6 to 1.6, with the maximum power coefficient Cp of 0.34 achieved at a TSR of 0.8. According to the numerical results based on the new CFD model, the presence of a bottom wall does not significantly affect the performance of a Savonius turbine. It means that the present unbounded CFD model can be acceptable in the initial design stage for the determination of the geometry parameters of a Savonius turbine.
Green and efficient biocatalytic technology has become a complementary or alternative means of organic synthesis. Chemicals with two functional groups, such as α,ω-dicarboxylic acids, ω-amino fatty acids and ω-hydroxy fatty acids, are widely used in the synthesis of polymers such as polyesters and polyamides. In recent years, the production of biodegradable materials using renewable and abundant vegetable oils as green raw materials has attracted increasing attention, receiving an additional impetus from synthetic biology. This paper presents the recent research progress in the production of bifunctional chemicals with medium chain lengths of C8–C12 using multi-enzyme cascades. Recent studies have developed multilevel optimization strategies to improve the efficiency, economics, and sustainability of multi-enzyme cascades. Cofactor regeneration strategies were developed to avoid large additions of expensive coenzymes. Protein engineering strategies were applied to improve enzyme stability and catalytic performance. In addition, blocking the β-oxidation pathway, improving the efficiency of substrate transport across membranes and increasing cellular robustness are effective optimization strategies for whole-cell catalytic systems. In addition, we discuss the development prospects of producing high value-added fine chemicals from vegetable oils using one-pot multi-enzyme reaction systems.
Fibrosis is defined by scarring and tissue hardening caused by excess deposition of extracellular matrix components, mainly collagens. A fibrotic response can occur in any tissue of the body and is the final outcome of an unbalanced reaction to inflammation and wound healing induced by a variety of insults, including persistent infections, autoimmune reactions, allergic responses, chemical exposure, radiation, and tissue injury. The accumulation of extracellular matrix proteins replaces the living tissue and disrupts the architecture leading to organ malfunction. Fibrosis remains a major clinical and therapeutic challenge and has been estimated to account for 45% of deaths in the developed world. While major advances regarding mechanistic knowledge on the underlying cell biology alterations in fibrosis have helped to characterize the main phases and mediators involved, this knowledge has not yielded significant progress in treatment. Only recently, the metabolic features associated to fibrosis have begun to emerge. This information, likely representing only the tip of the iceberg, suggests that metabolic derangement is a key culprit in the pathophysiology of fibrogenesis. The Workshop on The Cellular and Metabolic Bases of Organ Fibrosis, International University of Andalusia, Baeza, Spain, October 8–11, 2023 aimed to discuss the current knowledge and novel perspectives on the mechanisms contributing to the development of fibrosis in different organs and tissues, with particular focus on new methodological developments in metabolomics and therapeutic strategies.
Solar energy, as a clean source of energy, plays a relevant role in this much desired (r)evolution. When talking about photovoltaics, despite the multiple studies on parameters that affect the panels operation, concrete knowledge on this matter is still in an incipient stage and precise data remains dispersed, given the mutability of outer factors beyond technology-related properties, hence the difficulties associated with exploration. Wind is one of them. Wind loads can affect the temperature of photovoltaics, whose efficiency is reduced when higher temperatures are reached. The viability of wind as natural cooling mechanism for solar plants and its influence on their electrical energy production is studied in this research work. Some appropriate results were achieved: depending on the module temperature prediction model used and on the photovoltaic technology in question, solar panels are foreseen to be up to approximately 3% more productive for average wind speeds and up to almost 7% more productive for higher speeds. Taking into consideration that wind speed values were collected in the close vicinity of the modules, these results can be proven to be even higher. That being said, this article contributes with accurate insights about wind influence on electrical energy production of solar plants.
Tissue lymphatic vessels network plays critical roles in immune surveillance and tissue homeostasis in response to pathogen invasion, but how lymphatic system per se is remolded during infection is less understood. Here, we observed that influenza infection induces a significant increase of lymphatic vessel numbers in the lung, accompanied with extensive proliferation of lymphatic endothelial cells (LECs). Single-cell RNA sequencing illustrated the heterogeneity of LECs, identifying a novel PD-L1+ subpopulation that is present during viral infection but not at steady state. Specific deletion of Pd-l1 in LECs elevated the expansion of lymphatic vessel numbers during viral infection. Together these findings elucidate a dramatic expansion of lung lymphatic network in response to viral infection, and reveal a PD-L1+ LEC subpopulation that potentially modulates lymphatic vessel remolding.
The sustainable development concept is of crucial importance for the socioeconomic development processes, not only at the international community level, but also—or, perhaps, particularly—at the national or even local levels. The aim of the article is to demonstrate, from a legal-dogmatic perspective, the place, role and significance of the sustainable development concept in the Polish legal space. This perspective applies to both the state policy intended to formulate a strategy which provides a basis for law-making processes and to find normative solutions making it possible to reconcile legally protected values which sometimes compete with one another, with account taken of the needs of future generations. The sustainable development concept has been very broadly followed in Poland not only in the legal doctrine, but also in the doctrine of economic and social sciences. This term has turned out to be such an effective political catchword that it has been commonly abused and, therefore, it has lost a good deal of its social importance; this makes it substantially more difficult to apply a normative approach to the issues related to the implementation of the concept in legislative practice. In the Polish legal space, the sustainable development concept has become the leading theme of many documents and legal acts, particularly those concerned with environmental protection, but also, although to a much more modest extent, those addressing the issues of socioeconomic development.
Providing rapid, efficient, inexpensive, and resilient solutions is an eminent and urgent need for emergency relief conditions, mainly and increasingly driven by the impacts of climate change. Under such disastrous circumstances, the current practice involves preparation, dispatching and managing significant amounts of materials, resources, manpower, and transportation of basic needs, which can be hindered remarkably by infrastructure damage and massive loss of lives. However, an emerging technology known as 3D printing (3DP) can play a significant role and rapidly bring unlimited innovative solutions in such conditions with much lesser resources to meet the necessities of large populations affected. Considering the recent progress of 3DP technology and applications in different industrial and consumer sectors, this study aims to provide an analysis of the status and current progress of 3DP technology in various fields to understand and present its potential for readiness and response to disasters, emergency and relief need driven by climate change. Secondly, this study also presents a sustainability assessment of 3DP technology for such cases to evaluate economic, environmental, and social impacts. Finally, policies and strategies are suggested to adapt 3DP technology in different sectors to prepare for large-scale emergencies.