As power systems globally are transitioning from fossil fuels to renewable sources, integrating energy storage becomes imperative to balance variable renewable electricity generation. The core objective of this paper is to conduct a comprehensive cost assessment of selected energy storage technologies from 2023 to 2050, focusing on the Austrian electricity market. Our method combines techno-economic assessment with the technological learning method to integrate various storage technologies into a renewable electricity system, using scenarios that account for decarbonization goals. Results indicate that pumped storage hydro exhibits none or negative learning effects, while lithium-ion batteries demonstrate significant investment cost decreases. Despite investment cost reductions, underground hydrogen storage continues to incur high total costs per kWh discharged due to low roundtrip efficiency, suggesting its future outlook depends on seasonal storage needs in fossil-free power systems. An important finding of this analysis underscores the importance of optimizing the ratio of electricity demand, renewable generation expansion and storage deployment for cost-effectiveness. Excessive storage deployment leads to lower utilization and higher costs, emphasizing the necessity of at least 1500 full-load hours for profitable operation across all storage systems. Strategic planning for optimal storage deployment is emphasized to optimize utilization and minimize costs.
The article analyzes the main provisions of constructive anthropology developed in Russian empirio-criticism in the first quarter of the 20th century. The justification of non-metaphysical philosophy, which developed the “problematic” approach to cognition, made the new understanding of man possible. From this point of view, the essence of man is not a metaphysical constant, but is modeled on the basis of an appropriate organization of experience; the essence of man is determined by his existence and is constantly changing; the essence of man can be consciously adapted by directing his development and giving him the necessary characteristics; man as an essence is always man’s project, or scientific and philosophical concept; only by understanding man as a dynamic project can we justify free will and man’s capacity for creation. The project of constructive anthropology is fundamentally different from the philosophical anthropology developed in Germany in the 20th century by Max Scheler and Helmuth Plessner, since the latter is essentially an attempt to preserve the traditional metaphysical interpretation of man.
Wildfires have proven to be a significantly exigent issue over the past decades. An increasing amount of research has recently been focused on the use of Unmanned Aerial Vehicles (UAVs) and multi-UAV systems for wildfire monitoring. This work focuses on the development of a decentralized framework for the purpose of monitoring active wildfires and their surrounding areas with fixed wing UAVs. It proposes a distributed fire data update methodology, a new formation algorithm based on virtual forces, fine-tuned by a Genetic Algorithm (GA), to arrange virtual agents into the monitoring area, and a control strategy to safely and efficiently guide fixed wing UAVs to loiter over the structured virtual agents. The system is tested in Software In The Loop (SITL) simulation with up to eight UAVs. The simulation results demonstrate the effectiveness of the system in monitoring the fire in a persistent manner and providing updated situational awareness data. The experiments show that the proposed framework is able to achieve and maintain coverage up to 100% over the area of interest, and very accurate fire representation. However, the performance is decreased for the experiments with low UAV numbers and large fire sizes.
Idiopathic pulmonary fibrosis (IPF) is a type of interstitial pneumonia with an unknown cause that progresses gradually, primarily affecting the elderly. The presence of fibrosis has significant implications for individuals with reduced lung compliance, resulting in decreased quality of life and limited survival. Although the exact mechanism remains unclear, researchers have investigated various factors, such as senescent telomerase replication and abnormal lung stem cell differentiation, to understand the root cause. Extensive research has consistently shown that IPF is closely linked to the dysfunction of alveolar epithelial cells. Current scientific studies on IPF cover a range of aspects including oxidative stress, endoplasmic reticulum stress, mitochondrial damage, and iron-induced apoptosis. By examining these mechanisms, a comprehensive model has been developed that explains the process of IPF. Oxidative stress is identified as the primary trigger, followed by mitochondrial damage as a central component, leading to the mesenchymal transformation of alveolar epithelial cells as the ultimate outcome. This model is expected to serve as a valuable reference for understanding the mechanism of IPF and guiding future drug development efforts.
The direct conversion of methane into high-value chemicals has been a persistent research focus in the fields of chemical engineering and energy. Photocatalysis, as an innovative technology, not only circumvents the issues of catalyst sintering and carbon deposition associated with traditional thermal catalysis but also transcends thermodynamic limitations by providing new reaction pathways. Utilizing molecular oxygen as an oxidant generates various reactive oxygen species, offering unique thermodynamic advantages for methane conversion. This review summarizes the advancements in photocatalytic partial oxidation (PPOM) and oxidative coupling of methane (POCM) using oxygen as an oxidant. It discusses the activation mechanisms and reaction pathways of methane and oxygen in different systems, as well as the application of photochemical cycling strategies in methane conversion. Finally, it addresses the challenges in this field, proposes potential solutions, and offers perspectives on the future development of photocatalytic systems.
For more than 80 years, Spain has had a human rights problem. Since the 18th of July 1936, when military personnel and fascists staged a coup d’état against the democratic government of the Second Republic, thousands of victims remain missing. We will examine how the victims have been treated by the State and how civil society has led the process of recovering democratic memory. We will focus on its impact in the Bierzo region, in the northwest of the Iberian Peninsula, and its importance in this process. We will also look at how scientific efforts continue to search for missing persons. History, archaeology, physical anthropology, and genetics join forces to repair the victims of the Spanish Civil War and Franco’s dictatorship.
The title of this paper poses a paradoxical question, relating philosophy and humor, and tries to be humorous itself with the use of the verb “kill”. Against a more common, sometimes even academical, view of philosophy as a tremendously serious, deep, and complex corpus of knowledge—all theory and no praxis—the article challenges this view and will try to explain why humor, when associated with philosophy, can accelerate the understanding of a concept, and reveal unexpected spaces for reflection while donating moments of lightness and entertainment. In this perspective, humor reveals itself as a fundamental anthropological experience strongly connected to human freedom. I am aware that there are many different types of humor—irony, joke, slapstick, double-entendre, pun, deadpan-dry humor, etc., and also that the definition of “sense of humor” may be highly subjective, often related to the cultural profile of the person, and their geographical and historical contexts: what I consider funny, can be neutral or even offensive for another person. Nevertheless, among hundreds of interpretations, I will consider those which are more consistent with the scope of this paper. Moreover, if we think about the contemporary movement called philosophical counseling as a praxis that aims to help people in trouble and despair to see human problems from a wider and more rational Weltanschauung (view of the world), humor can become a useful tool to re-discover the frolicsome child inside ourselves: while playing with contrasts, metaphors, and metonymies, it induces a sudden, positive change of perspective. A process that is valid for both the counselor and the counselee, the self and the other: humor can provoke in the counselor a new and fresh way to understand the counselee’s difficulty; for the client, it can be a moment of tension release, or the start of a different way to address and approach life’s problems, or, even more, the beginning of a creative, transformative path.
Cellular Communication Network factors 1-6 (CCNs) are matricellular proteins consisting of an N-terminal secretory peptide and four multifunctional structural domains. The CCN1-6 members belonging to this family have a complex network of interacting ligands that can affect diverse signaling pathways through a multitude of mechanisms. Specifically, these proteins play crucial roles in cell proliferation, differentiation, angiogenesis, apoptosis, chondrogenesis, wound repair, and extracellular matrix (ECM) formation/remodeling. This short communication provides a brief summary of the 12th International Workshop on the CCN Family of Genes held at the Scandic Holmenkollen Park Hotel in Oslo, Norway from 20–23 June 2024.
A summary, based upon foresight, futures, ideation and frontier technology studies of prospective approaches to foster ecosystem sustainability including climate mitigation at the technology and societal levels which are at scale and profitable. Approaches summarized include halophytes/salt plants grown on deserts/wastelands using saline/seawater, to address land, water, food, energy and climate, frontier energetics, nascent climate mitigation concepts, cellular agriculture, materials optimization, the virtual age, efficiency and redesigning the ecosystem for the Anthropocene. Solution/mitigation approaches are targeted at deforestation, desertification, pollution writ large (land, sea, air, space), and extensive urbanization along with soil salination, ocean acidification, mining, and water scarcity.