Machine Learning Approaches
to Identify and Classify ADHD: A Narrative Review with Tabular Performance
Synthesis and Human–AI Mapping
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ABSTRACT:
Attention-Deficit/Hyperactivity
Disorder (ADHD) presents diagnostic challenges due to heterogeneity,
comorbidity rates, and reliance on subjective, phenomenological criteria,
resulting in misdiagnosis or treatment delays. This structured narrative review
with quantitative tabular synthesis, conceptual mapping, and clinical workflow
integration employed a sunflower life-cycle metaphor to bridge clinical
expertise and machine learning (ML) technologies, while surveying recent
empirical studies (2017–2023) to capture methodological variation in ADHD
assessment workflows. Ten studies were selected based on relevance to ML
applications for ADHD identification and classification, with deliberate
representation of diversity in study design, sample characteristics, data
modalities, and ML model-type. The method comprised (a) broad interpretive
literature searches, (b) extraction of study-level data, and (c) mapping of ML
approaches onto a standardized evidence-based ADHD assessment workflow.
Analyses included qualitative synthesis of sample characteristics
(youth-focused, N = 38–238,696),
data modalities (behavioral surveys, EHR, neuroimaging, genetics), ML models
(RF, SVM, DNN), performance metrics, phenotype- and genotype-based
distinctions; quantitative aggregation of reported performance metrics
(accuracy 66–93%, AUC 0.66–0.94); cross-validation practice, and model-level
considerations; and tabular summarization of limitations and multidimensional
predictors. Syntheses produced comparative tables, a human–AI diagnostic
workflow diagram, and explicit alignment of ML applications with each clinical
stage to highlight integration points and gaps.
Keywords:
Attention deficit disorder
with hyperactivity; Machine learning; Decision
support techniques; Diagnosis; Algorithms